Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858702 | 0.93 | DRD2 (0.53) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5858700 | 0.90 | TACR2 (0.52) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5860261 | 0.88 | SLC6A4 (0.52) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5858744 | 0.87 | DRD2 (0.68) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5857960 | 0.83 | DRD2 (0.54) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5860221 | 0.82 | SLC6A4 (0.53) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5860215 | 0.82 | TACR2 (0.45) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5860217 | 0.80 | DRD2 (0.50) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5857199 | 0.79 | DRD2 (0.49) | DRD2SLC6A4TACR2CYP2D6CCR5 | |
| SCHEMBL5857996 | 0.78 | SLC6A4 (0.50) | DRD2SLC6A4TACR2CYP2D6CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989393-B2 | Ccr5 modulators benzimidazoles or benzotriazoles | ASTRAZENECA AB (SE) | 2006-01-24 | — | — | US | disclosed |