SCHEMBL5858852

SCHEMBL5858852

Cc1ccc(C(OB(O)O)(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
CA2 P00918 2/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41
ACHE P22303 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP19A1 P11511 1/20 0.35
CA1 P00915 2/20 0.34
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
MLYCD O95822 1/20 0.33
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetramethylammonium Ion SCHEMBL8398492 0.94 TSHR (0.38) TSHRCA2LPLLIPGORAI1
Tetrylammonium SCHEMBL8397609 0.87 TSHR (0.33) TSHRCA2LPLLIPGORAI1
SCHEMBL8714160 0.83 KDM1A (0.38) TSHR
SCHEMBL8647123 0.82 LMNA (0.46) TSHRCA2TDP1CA1NPC1
Tetrabuthylammonium SCHEMBL8399157 0.82 SLC22A1 (0.36) TSHRALDH1A1LMNA
SCHEMBL8398751 0.80 SLC22A1 (0.38) TSHRALDH1A1LMNA
SCHEMBL723986 0.76 KIF11 (0.40) TSHRCA2ORAI1ORAI2ORAI3
SCHEMBL8784448 0.70 TSHR (0.50) TSHRCA2ACHETDP1CYP19A1
SCHEMBL3867443 0.69 TSHR (0.48) TSHRCA2ACHETDP1CYP19A1
P-Xylene SCHEMBL14874707 0.68 ACHE (0.67) TSHRCA2LPLLIPGORAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7087353-B2 Non-contact heat fixing toner KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2006-08-08 US disclosed
US-20040142263-A1 Non-contact heat fixing toner KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. 2004-07-22 US disclosed
EP-0613058-B1 Light-decolorizable recording material SHOWA DENKO KK (JP) 1999-06-02 EP disclosed
US-5846682-A Light decolorizable recording material, ink and toner SHOWA DENKO K.K. (JP) 1998-12-08 US disclosed
EP-0661598-B1 Decolorizable toner and a decolorizable toner production process SHOWA DENKO KK (JP) 1998-09-16 EP disclosed
US-5607803-A Decolorizable toner and a decolorizable toner production process SHOWA DENKO K.K. (JP) 1997-03-04 US disclosed
EP-0661598-A1 Decolorizable toner and a decolorizable toner production process SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-07-05 EP disclosed
EP-0613058-A1 Light-decolorizable recording material SHOWA DENKO KABUSHIKI KAISHA (JP) 1994-08-31 EP disclosed