SCHEMBL5859124

SCHEMBL5859124

C#CCCCOc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.49
NR5A1 Q13285 1/20 0.49
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
ABCG2 Q9UNQ0 3/20 0.43
ESR2 Q92731 1/20 0.42
APP P05067 1/20 0.41
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10394871 0.94 LTA4H (0.53) LTA4HNR5A1DRD2DRD4DRD3
SCHEMBL24894106 0.87 NR5A1 (0.59) LTA4HNR5A1DRD2DRD4DRD3
SCHEMBL14901605 0.79 GSTP1 (0.58) LTA4HCA12CA9MAOAMAOB
SCHEMBL7364135 0.79 HDAC1 (0.54)
SCHEMBL28904092 0.77 HDAC1 (0.54)
SCHEMBL688720 0.77 LTA4H (0.55) LTA4HNR5A1DRD2DRD4DRD3
SCHEMBL12517392 0.77 LTA4H (0.55) LTA4HNR5A1DRD2DRD4DRD3
SCHEMBL428018 0.77 LTA4H (0.78) LTA4HNR5A1ABCG2ESR2CYP3A4
SCHEMBL2924048 0.77 ALDH1A1 (0.58) LTA4HNR5A1DRD2DRD4DRD3
SCHEMBL10880112 0.76 HRH3 (0.49) LTA4HCA12CA9MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7070712-B2 Acetylene polymers and their use as liquid crystals THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (HK) 2006-07-04 US disclosed
US-20060022169-A1 Acetylene polymers and their use as liquid crystals THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (HK) 2006-02-02 US disclosed
US-20040140449-A1 Acetylene polymers and their use as liquid crystals THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (HK) 2004-07-22 US disclosed
US-20030164474-A1 Acetylene polymers and their use as liquid crystals THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY 2003-09-04 US disclosed
US-20020033474-A1 Acetylene polymers and their use as liquid crystals TANG BEN ZHONG (HK) 2002-03-21 US disclosed