⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775163 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL28110144 | 0.74 | — | — | |
| SCHEMBL1481797 | 0.71 | — | — | |
| SCHEMBL6971162 | 0.71 | — | — | |
| SCHEMBL243682 | 0.71 | — | — | |
| SCHEMBL6423396 | 0.71 | DGKA (0.36) | — | |
| SCHEMBL10010450 | 0.69 | — | — | |
| SCHEMBL7627037 | 0.67 | TSHR (0.44) | — | |
| SCHEMBL3985200 | 0.67 | — | — | |
| SCHEMBL1140911 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |
| EP-2691373-A1 | 3-UREIDOISOQUINOLIN-8-YL DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012131588-A1 | 3-UREIDOISOQUINOLIN-8-YL DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012075117-A2 | SMALL MOLECULE-POLYMER CONJUGATES AND METHODS OF MAKING SAME | ABLITECH, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012075114-A2 | NUCLEIC ACID-POLYMER CONJUGATES AND USES THEREOF | ABLITECH, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| EP-2437789-A1 | BIOMOLECULE-POLYMER CONJUGATES AND METHODS OF MAKING SAME | Ablitech, Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| EP-2417172-A1 | DIBLOCK COPOLYMER MODIFIED NANOPARTICLE/POLYMER COMPOSITES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010141507-A1 | BIOMOLECULE-POLYMER CONJUGATES AND METHODS OF MAKING SAME | ABLITECH, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010118343-A1 | DIBLOCK COPOLYMER MODIFIED NANOPARTICLE/POLYMER COMPOSITES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |