Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860207 | 0.89 | CYP2C9 (0.43) | ALDH1A1CYP2C9KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5862246 | 0.85 | CYP2C9 (0.41) | CYP46A1ALDH1A1CYP2C9KDM4EKMT2A | |
| SCHEMBL5859244 | 0.78 | CYP46A1 (0.44) | CYP46A1ALDH1A1CYP2C9KDM4EKMT2A | |
| SCHEMBL5859070 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1CYP2C9TSHRHPGDSMN1; SMN2 | |
| SCHEMBL5859955 | 0.77 | CYP2C9 (0.43) | ALDH1A1CYP2C9KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5859258 | 0.76 | ALDH1A1 (0.40) | CYP46A1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL5859929 | 0.76 | TDP1 (0.41) | TSHRSMN1; SMN2GLAHTTTDP1 | |
| SCHEMBL5859235 | 0.75 | CYP2C9 (0.45) | ALDH1A1CYP2C9KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5859859 | 0.74 | TDP1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL5859049 | 0.74 | ROCK1 (0.47) | ALDH1A1CYP2C9KDM4EKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |