Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859859 | 0.92 | TDP1 (0.46) | TDP1RAB9ASMN1; SMN2GLAPOLB | |
| SCHEMBL5862246 | 0.91 | CYP2C9 (0.41) | TDP1TSHRRAB9AHTT | |
| SCHEMBL6661310 | 0.90 | ALDH1A1 (0.47) | TDP1TSHRRAB9ASMN1; SMN2GLA | |
| SCHEMBL5862104 | 0.90 | PLAUR (0.44) | TSHRRAB9A | |
| SCHEMBL5859235 | 0.88 | CYP2C9 (0.45) | TDP1SMN1; SMN2HTT | |
| SCHEMBL5859070 | 0.83 | SMN1; SMN2 (0.45) | TDP1TSHRRECQLRAB9ASMN1; SMN2 | |
| SCHEMBL5859208 | 0.83 | PDE4B (0.43) | RECQLPOLBHTT | |
| SCHEMBL5859916 | 0.82 | RAB9A (0.49) | RAB9ASMN1; SMN2POLBNPC1 | |
| SCHEMBL5859258 | 0.81 | ALDH1A1 (0.40) | TSHRRAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL5859907 | 0.81 | RAB9A (0.49) | RAB9ASMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |