Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL602444 | 0.84 | TSHR (0.52) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL29672221 | 0.84 | TSHR (0.52) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL1770903 | 0.81 | ALDH1A1 (0.49) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL29435964 | 0.81 | ALDH1A1 (0.49) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL1770886 | 0.79 | TSHR (0.47) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL29672268 | 0.79 | ALDH1A1 (0.47) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL313585 | 0.79 | ALDH1A1 (0.49) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL29937444 | 0.79 | TSHR (0.47) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL1024954 | 0.79 | ALDH1A1 (0.47) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL10400092 | 0.79 | TSHR (0.47) | CYP3A4TSHRALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012146-B2 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2006-03-14 | — | — | US | claimed |
| US-20020169203-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-11-14 | — | — | US | claimed |
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169203-A1 | Ion channel modulating agents | KCNN3, KCNN1, KCNN2 | CYP3A4 4157/4885TSHR 4434/4885ALDH1A1 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.