Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672221 | 1.00 | TSHR (0.52) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL7617600 | 0.89 | CYP3A4 (0.52) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1770903 | 0.85 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL29435964 | 0.85 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL29672268 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1770886 | 0.84 | TSHR (0.47) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL29937444 | 0.84 | TSHR (0.47) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL5860481 | 0.84 | CYP3A4 (0.47) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL313585 | 0.84 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1024954 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184577-B | Phenyl ether meta-amide compound and application thereof | 山东省农药科学研究院 | 2024-07-23 | — | — | CN | claimed |
| CN-118184577-A | Phenyl ether meta-amide compound and application thereof | 山东省农药科学研究院 | 2024-06-14 | — | — | CN | claimed |
| JP-60123471-A | — | — | None | — | — | JP | disclosed |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2026-01-22 | — | — | US | disclosed |
| US-12479834-B2 | Phenol compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2025-11-25 | — | — | US | disclosed |
| CN-118184577-B | Phenyl ether meta-amide compound and application thereof | 山东省农药科学研究院 | 2024-07-23 | — | — | CN | disclosed |
| CN-118184577-A | Phenyl ether meta-amide compound and application thereof | 山东省农药科学研究院 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023229346-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | 주식회사 체크메이트테라퓨틱스 | 2023-11-30 | — | — | WO | disclosed |
| US-20230049402-A1 | NOVEL PHENOL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 2023-02-16 | — | — | US | disclosed |
| EP-4067343-A1 | NOVEL PHENOL COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2022-10-05 | — | — | EP | disclosed |
| WO-2022101265-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-19 | — | — | WO | disclosed |
| EP-0162776-A2 | Heterocyclic derivatives, process for their preparation and medicaments useful as aldose reductase inhibitors containing them | LABORATOIRES UPSA (FR) | 1985-11-27 | — | — | EP | disclosed |
| JP-S60123471-A | PRODUCTION OF N-(3-CHLORO-5-TRIFLUOROMETHYL-2-PYRIDYL)-3- CHLORO-2,6-DINITRO-4-TRIFLUOROMETHYLANILINE | ISHIHARA SANGYO KAISHA LTD | 1985-07-02 | — | — | JP | disclosed |
| EP-0000542-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL PHENOLS | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4225731-A | Process for the preparation of trifluoromethylphenols | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004623-A1 | Process for the preparation of aromatic amines | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |
| EP-0000542-A1 | Process for the preparation of trifluoromethyl phenols | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| US-3989707-A | NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-02 | — | — | US | disclosed |
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954788-A | INTERMEDIATES FOR HERBIDIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479834-B2 | Phenol compound or salt thereof | REN, MLX, MYB | TSHR 1888/4885ALDH1A1 287/4885CYP3A4 2867/4885 |
| US-20230049402-A1 | NOVEL PHENOL COMPOUND OR SALT THEREOF | MYB, MLX, EP300 | TSHR 2462/4885ALDH1A1 235/4885CYP3A4 3428/4885 |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | NAMPT, NAPRT, NNT | TSHR 1450/4885ALDH1A1 789/4885CYP3A4 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.