Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7939816 | 0.77 | HTR6 (0.32) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6732155 | 0.74 | HTR6 (0.31) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL4469697 | 0.73 | SIGMAR1 (0.36) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6720598 | 0.71 | HTR6 (0.30) | HTR6HTR2A | |
| SCHEMBL7026621 | 0.71 | SIGMAR1 (0.37) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8853869 | 0.70 | SIGMAR1 (0.36) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8830369 | 0.70 | SIGMAR1 (0.36) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8853875 | 0.70 | SIGMAR1 (0.36) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL29479969 | 0.70 | SIGMAR1 (0.36) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7951350 | 0.70 | HTR2A (0.36) | SIGMAR1HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336127-B2 | Process for preparing poly-alpha-olefins | HOECHST AG (DE) | 1997-04-09 | — | — | EP | claimed |
| US-7026401-B1 | Method of producing amorphous polyolefins with a wide mole weight distribution | TICONA GMBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-5874505-A | Polypropylene composition | CHISSO CORPORATION (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5679811-A | Hafnium metallocene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |