Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084121 | 0.80 | LMNA (0.62) | ALDH1A1ALDH1A2ALDH2ALDH3A1ALDH1A3 | |
| SCHEMBL5858830 | 0.78 | GRM2 (0.69) | ALDH1A1ALDH2ALDH3A1SLC9A1GRM2 | |
| SCHEMBL5861811 | 0.77 | SLC9A1 (0.65) | SLC9A1HPGDTSHRKMT2AGAA | |
| SCHEMBL5859932 | 0.76 | SLC9A1 (0.51) | ALDH1A1SLC9A1GRM2KCNMA1LMNA | |
| SCHEMBL5858757 | 0.76 | SLC9A1 (0.48) | ALDH1A1SLC9A1GRM2KCNMA1LMNA | |
| SCHEMBL5859138 | 0.76 | TSHR (0.65) | ALDH1A1SLC9A1GRM2LMNATP53 | |
| SCHEMBL5859945 | 0.76 | SLC9A1 (0.48) | ALDH1A1SLC9A1GRM2KCNMA1LMNA | |
| SCHEMBL5858823 | 0.76 | POLB (0.48) | ALDH1A1SLC9A1GRM2KCNMA1LMNA | |
| SCHEMBL5859703 | 0.76 | KDM4E (0.49) | ALDH1A1LMNAKMT2AGAA | |
| Hydrochloric Acid SCHEMBL5859906 | 0.75 | POLB (0.47) | ALDH1A1SLC9A1GRM2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030140-B2 | Substituted benzimidazole antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-6908936-B2 | Substituted benzimidazole antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-21 | — | — | US | disclosed |
| US-20050038085-A1 | Substituted benzimidazole antiviral agents | YU KUO-LONG (US) | 2005-02-17 | — | — | US | disclosed |
| US-20030139450-A1 | Substituted benzimidazole antiviral agents | YU KUO-LONG (US) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038085-A1 | Substituted benzimidazole antiviral agents | MAVS, ZC3HAV1, ZC3HAV1L | ALDH1A1 1674/4885ALDH1A2 3485/4885ALDH2 710/4885 |
| US-20030139450-A1 | Substituted benzimidazole antiviral agents | MAVS, ZC3HAV1, ZC3HAV1L | ALDH1A1 1674/4885ALDH1A2 3485/4885ALDH2 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.