Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862113 | 0.89 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9872559 | 0.86 | DRD4 (0.78) | SIGMAR1 | |
| SCHEMBL24514573 | 0.85 | POLB (0.74) | SIGMAR1 | |
| SCHEMBL8037825 | 0.84 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL5862050 | 0.84 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8035540 | 0.84 | SIGMAR1 (1.00) | SIGMAR1TMEM97 | |
| SCHEMBL9727102 | 0.84 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL13929323 | 0.83 | CCR5 (0.73) | SIGMAR1 | |
| SCHEMBL5862025 | 0.83 | SIGMAR1 (0.70) | SIGMAR1TMEM97 | |
| SCHEMBL9727061 | 0.81 | SIGMAR1 (0.74) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041667-B1 | CCR5 modulators | PFIZER, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1013276-A1 | Aminoazacycloalkanes as CCR5 modulators | PFIZER INC. (US) | 2000-06-28 | — | — | EP | disclosed |