SCHEMBL5862340

SCHEMBL5862340

CCCCOc1ccc(C(C)(C)C)cc1S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.37
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ENPP1 P22413 1/20 0.36
NR1I2 O75469 2/20 0.35
PTPN1 P18031 1/20 0.35
MAPK1 P28482 1/20 0.35
RAPGEF3 O95398 2/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
MMP1 P03956 1/20 0.34
MMP7 P09237 1/20 0.34
ACE P12821 1/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
WDR5 P61964 1/20 0.34
KAT6A Q92794 1/20 0.34
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5861614 0.97 PTPN1 (0.38) GAATDP1L3MBTL1ENPP1NR1I2
SCHEMBL5861677 0.96 PTPN1 (0.39) GAATDP1L3MBTL1NR1I2PTPN1
SCHEMBL5862339 0.88 RAPGEF3 (0.41) GAATDP1L3MBTL1MAPK1RAPGEF3
SCHEMBL5861707 0.88 ALDH1A1 (0.41) GAANR1I2MAPK1ALDH1A1HSD17B10
SCHEMBL5861991 0.85 RAPGEF3 (0.38) GAATDP1L3MBTL1PTPN1RAPGEF3
SCHEMBL5862996 0.85 S1PR3 (0.39) GAATDP1L3MBTL1PTPN1RAPGEF3
SCHEMBL5862000 0.84 ALDH1A1 (0.41) GAAMAPK1ALDH1A1HSD17B10POLB
SCHEMBL5861729 0.83 ESR1 (0.41) GAANR1I2MAPK1ALDH1A1HSD17B10
SCHEMBL5862968 0.83 ESR1 (0.41) GAANR1I2MAPK1ALDH1A1HSD17B10
SCHEMBL5862347 0.83 ESR1 (0.41) GAANR1I2MAPK1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109311-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process POLL, VEGFA, PIM3 GAA 1960/4885TDP1 1060/4885L3MBTL1 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.