SCHEMBL5862424

SCHEMBL5862424

c1coc(Cc2ccc(Cc3ccco3)o2)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.41
ALDH1A1 P00352 5/20 0.39
USP2 O75604 2/20 0.38
GAA P10253 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALOX5 P09917 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EPHX2 P34913 2/20 0.36
POLB P06746 1/20 0.36
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12442326 0.89 ALDH1A1 (0.38) CHRM2ALDH1A1GAATDP1ALOX5
SCHEMBL1404275 0.89 CHRM2 (0.46) CHRM2ALDH1A1USP2GAATDP1
SCHEMBL15978546 0.89 ALDH1A1 (0.38) CHRM2ALDH1A1USP2GAATDP1
SCHEMBL15371815 0.89 ALDH1A1 (0.38) CHRM2ALDH1A1GAATDP1ALOX5
SCHEMBL2266485 0.85 POLB (0.47) CHRM2ALDH1A1TDP1HPGDKMT2A
SCHEMBL15977333 0.84 NPC1 (0.42) CHRM2ALDH1A1USP2GAAHPGD
SCHEMBL20746903 0.84 CYP2E1 (0.40) CHRM2ALDH1A1GAATDP1CYP3A4
SCHEMBL3408691 0.79 TDP1 (0.55) TDP1KMT2AMEN1TSHRMAPT
SCHEMBL28075437 0.76 HTT (0.47) ALDH1A1GAATSHRPOLB
SCHEMBL7519576 0.76 ALDH1A1 (0.53) CHRM2ALDH1A1USP2GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092821-B2 Medical devices having polymeric regions with improved adhesion BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-01-10 US disclosed
US-8092821-B2 Medical devices having polymeric regions with improved adhesion BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-01-10 US disclosed
US-7897170-B2 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-01 US disclosed
US-7897171-B2 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-01 US disclosed
US-7897170-B2 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-01 US disclosed
US-7897171-B2 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-01 US disclosed
US-20090186067-A1 MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-07-23 US disclosed
US-20090186067-A1 MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-07-23 US disclosed
US-20080051542-A1 Medical devices having polymeric regions with improved adhesion STRICKLER FREDERICK H 2008-02-28 US disclosed
US-20080051541-A1 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. 2008-02-28 US disclosed
US-20080051542-A1 Medical devices having polymeric regions with improved adhesion STRICKLER FREDERICK H 2008-02-28 US disclosed
US-20080051541-A1 Medical devices having improved mechanical performance BOSTON SCIENTIFIC SCIMED, INC. 2008-02-28 US disclosed
EP-1483303-B1 METHOD FOR THE PRODUCTION OF ISOBUTENE POLYMERS BASF AG (DE) 2006-05-31 EP disclosed
US-7001966-B2 Method for the production of isobutene polymers BASF AKTIENGESELLSCHAFT (DE) 2006-02-21 US disclosed
US-20050107551-A1 Method for the production of isobutene polymers BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed
EP-1483303-A1 METHOD FOR THE PRODUCTION OF ISOBUTENE POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-12-08 EP disclosed
WO-2003074577-A1 METHOD FOR THE PRODUCTION OF ISOBUTENE POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2003-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186067-A1 MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE PIGS, TNNI3, TNNC1 CHRM2 3201/4885ALDH1A1 4108/4885USP2 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.