Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 8/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124688 | 0.95 | OPRM1 (0.41) | EPHA2OPRM1OPRK1NTMT1 | |
| SCHEMBL10340262 | 0.93 | ACE (0.42) | EPHA2OPRM1OPRK1NTMT1APLNR | |
| SCHEMBL4190057 | 0.93 | ACE (0.42) | EPHA2OPRM1OPRK1NTMT1APLNR | |
| SCHEMBL4190053 | 0.93 | ACE (0.42) | EPHA2OPRM1OPRK1NTMT1APLNR | |
| SCHEMBL27445701 | 0.93 | ACE (0.42) | EPHA2OPRM1OPRK1NTMT1APLNR | |
| SCHEMBL7444428 | 0.93 | ACE (0.42) | EPHA2OPRM1OPRK1NTMT1APLNR | |
| SCHEMBL31124690 | 0.92 | OPRM1 (0.43) | EPHA2OPRM1OPRK1 | |
| SCHEMBL7853147 | 0.91 | DPP4 (0.41) | DPP4OPRM1OPRK1NTMT1 | |
| SCHEMBL15524993 | 0.91 | DPP4 (0.41) | DPP4OPRM1OPRK1NTMT1 | |
| SCHEMBL9577364 | 0.91 | DPP4 (0.41) | DPP4OPRM1OPRK1NTMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045585-B2 | Methods of coating a device using anti-thrombin heparin | HAMILTON CIVIC HOSPITAL RESEARCH DEVELOPMENT INC. (CA) | 2006-05-16 | — | — | US | disclosed |
| US-20030124705-A1 | Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates | MCMASTER UNIVERSITY (CA) | 2003-07-03 | — | — | US | disclosed |