Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445701 | 1.00 | ACE (0.42) | ACEOPRM1OPRK1RENNTMT1 | |
| SCHEMBL4190053 | 1.00 | ACE (0.42) | ACEOPRM1OPRK1RENNTMT1 | |
| SCHEMBL10340262 | 1.00 | ACE (0.42) | ACEOPRM1OPRK1RENNTMT1 | |
| SCHEMBL4190057 | 1.00 | ACE (0.42) | ACEOPRM1OPRK1RENNTMT1 | |
| Acetic Acid SCHEMBL31151814 | 0.97 | OPRM1 (0.42) | ACEOPRM1OPRK1RENEPHA2 | |
| SCHEMBL30138485 | 0.96 | CAPN1 (0.40) | ACEOPRM1OPRK1EPHA2APLNR | |
| SCHEMBL31124688 | 0.94 | OPRM1 (0.41) | ACEOPRM1OPRK1NTMT1EPHA2 | |
| SCHEMBL5863304 | 0.93 | EPHA2 (0.41) | OPRM1OPRK1NTMT1EPHA2APLNR | |
| SCHEMBL29568888 | 0.93 | APLNR (0.42) | ACEOPRM1OPRK1EPHA2APLNR | |
| SCHEMBL31124685 | 0.92 | ITGB3 (0.42) | OPRM1OPRK1NTMT1EPHA2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |