SCHEMBL384438

SCHEMBL384438

O=C(Cl)CCCCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
HDAC1 Q13547 6/20 0.61
HDAC2 Q92769 4/20 0.61
HDAC3 O15379 3/20 0.61
HDAC8 Q9BY41 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61
HDAC5 Q9UQL6 3/20 0.61
HDAC4 P56524 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC10 Q969S8 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
MAPK1 P28482 1/20 0.61
ADRA1A P35348 1/20 0.61
SLC6A3 Q01959 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALOX5 P09917 3/20 0.59
FAAH O00519 3/20 0.58
CES1 P23141 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7768077 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL7883758 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL9664667 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL3250759 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL5793035 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL9664005 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL3253249 0.98 MAPT (0.71) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL61491 0.94 HDAC1 (0.69) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL8772423 0.93 MAPT (0.82) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL27538484 0.92 HDAC1 (0.67) MAPTRXFP1HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250009285-A1 PRE-SEIZURE DETECTION DEVICE INCORPORATING ELECTRONIC NOSE TECHNOLOGY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2025-01-09 US claimed
US-4272502-A Process for preparing gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1981-06-09 US claimed
EP-4692061-A1 LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF Aevis Bio, Inc. (KR) 2026-02-11 EP disclosed
US-20250288559-A1 PREP BINDING LIGANDS POLKU THERAPEUTICS OY (FI) 2025-09-18 US disclosed
EP-4514781-A1 PREP BINDING LIGANDS Polku Therapeutics OY (FI) 2025-03-05 EP disclosed
CN-119451944-A PREP binding ligands 珀尔库治疗有限公司 2025-02-14 CN disclosed
US-20250009285-A1 PRE-SEIZURE DETECTION DEVICE INCORPORATING ELECTRONIC NOSE TECHNOLOGY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2025-01-09 US disclosed
WO-2024205319-A1 LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF 주식회사 아이비스바이오 2024-10-03 WO disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20230364272-A1 THERANOSTIC COMPOUNDS UNIVERSITY OF CAPE TOWN (ZA) 2023-11-16 US disclosed
US-20230364272-A1 THERANOSTIC COMPOUNDS UNIVERSITY OF CAPE TOWN (ZA) 2023-11-16 US disclosed
EP-0273451-A2 Lipoxygenase inhibitory compounds Bristol-Myers Squibb Company (US) 1988-07-06 EP disclosed
US-4705802-A Omega-aryl-alkylthienyl-compounds and process for the treatment of chronically inflammatory processes in humans A. NATTERMANN & CIE GMBH (DE) 1987-11-10 US disclosed
EP-0201741-A2 Dipeptide derivatives, processes for preparing them, pharmaceutical composition and use SUNTORY LIMITED (JP) 1986-11-20 EP disclosed
EP-0155524-A1 -Omega-aryl-alkylthienyl compounds, process for their preparation and pharmaceutical products containing these compounds A. Nattermann & Cie. GmbH (DE) 1985-09-25 EP disclosed
US-4272502-A Process for preparing gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1981-06-09 US disclosed
EP-0019699-A1 Process for the production of gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HÜLS AG (DE) 1980-12-10 EP disclosed
EP-0014386-A2 Phosphoramido(di)thioate derivatives, processes for their preparation and pesticidal compositions containing them, as well as intermediates ROHM AND HAAS COMPANY (US) 1980-08-20 EP disclosed
US-3992396-A TRANQUILIZERS, HYPNOTICS SANDOZ, INC. (US) 1976-11-16 US disclosed
US-3984501-A PROSTAGLANDIN INHIBITORS NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364272-A1 THERANOSTIC COMPOUNDS MMP12, TIMP3, CTSZ MAPT 689/4885RXFP1 1884/4885HDAC1 125/4885
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 MAPT 3228/4885RXFP1 239/4885HDAC1 4258/4885
US-20250288559-A1 PREP BINDING LIGANDS PREP, ERAP2, CTSA MAPT 326/4885RXFP1 3141/4885HDAC1 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.