Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 8/20 | 0.36 |
| ▸ | CCND1 | P24385 | 8/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863449 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL5864145 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL5864286 | 0.74 | HTR2C (0.51) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL5863900 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTHTT | |
| SCHEMBL5864100 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10CASP1CASP7 | |
| SCHEMBL24861134 | 0.67 | CRBN (0.53) | ALDH1A1HTTABL1CDK4CCND1 | |
| SCHEMBL31672239 | 0.67 | CRBN (0.53) | ALDH1A1HTTABL1CDK4CCND1 | |
| SCHEMBL21333743 | 0.66 | MAPT (0.50) | ALDH1A1MAPTHTTCDK4CCND1 | |
| SCHEMBL24861331 | 0.65 | CRBN (0.41) | ABL1CDK4CCND1FGFR1FGFR2 | |
| SCHEMBL14966121 | 0.64 | BRD4 (0.46) | ALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030120-B2 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | OHKURA NAOTO (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6777414-B1 | INHIBITORS OF TRIGLYCERIDE BIOSYNTHESIS AND SECRETION OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; ARTERIOSCLEROTIC DISEASES; HYPERLIPIDEMIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1180514-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2002-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | APOB, NCEH1, LIPC | ALDH1A1 1345/4885KDM4E 2536/4885HSD17B10 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.