Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531554 | 1.00 | EPHX2 (0.42) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL5922012 | 0.85 | EPHX2 (0.34) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL3778927 | 0.84 | ALDH1A1 (0.32) | EPHX2LMNAHTTNPSR1MEN1 | |
| SCHEMBL8157774 | 0.83 | MEN1 (0.35) | EPHX2LMNAHTTNPSR1MEN1 | |
| SCHEMBL9364485 | 0.83 | ALDH1A1 (0.33) | EPHX2LMNAHTTNPSR1MEN1 | |
| SCHEMBL901494 | 0.83 | EPHX2 (0.39) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL2029635 | 0.82 | KMT2A (0.39) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL21799353 | 0.82 | KMT2A (0.39) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL20357288 | 0.82 | KMT2A (0.39) | EPHX2LMNAHTTNPSR1MAPT | |
| SCHEMBL26529 | 0.82 | KMT2A (0.39) | EPHX2LMNAHTTNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138139-B2 | Tablet coating | ROHM AND HAAS COMPANY (US) | 2006-11-21 | — | — | US | disclosed |
| US-20040121934-A1 | Polymeric detergent additives | DOUGHERTY RICHARD CHARLES (US) | 2004-06-24 | — | — | US | disclosed |