SCHEMBL901494

SCHEMBL901494

C=C(C(=O)O)C(CC)CCCCCC.CC(=CC1CC2CCC1(C)C2(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.39
LMNA P02545 4/20 0.33
HTT P42858 4/20 0.33
NPSR1 Q6W5P4 3/20 0.33
MAPT P10636 2/20 0.33
CPB2 Q96IY4 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PLA2G1B P04054 1/20 0.33
MAPK1 P28482 1/20 0.33
RAD52 P43351 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5864543 0.83 EPHX2 (0.42) EPHX2LMNAHTTNPSR1MAPT
SCHEMBL2531554 0.83 EPHX2 (0.42) EPHX2LMNAHTTNPSR1MAPT
SCHEMBL5799834 0.79 CYP2C19 (0.42) EPHX2LMNAHTTNPSR1MAPT
SCHEMBL2029635 0.78 KMT2A (0.39) EPHX2LMNAHTTNPSR1MAPT
SCHEMBL3778927 0.72 ALDH1A1 (0.32) EPHX2LMNAHTTNPSR1MEN1
SCHEMBL4638076 0.71 CA2 (0.53) MAPTMAPK1
SCHEMBL148742 0.71 CA2 (0.53) MAPTMAPK1
SCHEMBL21603036 0.71 CA2 (0.53) MAPTMAPK1
SCHEMBL1776563 0.71 CA2 (0.53) MAPTMAPK1
SCHEMBL5922012 0.71 EPHX2 (0.34) EPHX2LMNAHTTNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9428669-B2 Two-part polyurethanes based on hyperbranched polymers SIKA TECHNOLOGY AG (CH) 2016-08-30 US disclosed
EP-2331643-B1 AQUEOUS COATING COMPOSITION COATINGS FOREIGN IP CO LLC (US) 2014-03-05 EP disclosed
US-20130210998-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS SIKA TECHNOLOGY AG (CH) 2013-08-15 US disclosed
EP-2621989-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS Sika Technology AG (CH) 2013-08-07 EP disclosed
WO-2012041951-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS SIKA TECHNOLOGY AG (CH) 2012-04-05 WO disclosed
EP-2331643-A1 AQUEOUS COATING COMPOSITION E. I. du Pont de Nemours and Company (US) 2011-06-15 EP disclosed
WO-2010028123-A1 AQUEOUS COATING COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-11 WO disclosed
US-20100056724-A1 PROCESS FOR PREPARATION OF AQUEOUS BINDER LATICES AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2010-03-04 US disclosed
US-20100056706-A1 AQUEOUS COATING COMPOSITION AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2010-03-04 US disclosed