Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593459 | 1.00 | LMNA (0.50) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9228374 | 0.96 | LMNA (0.44) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL15789011 | 0.90 | LMNA (0.47) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9712157 | 0.87 | LMNA (0.45) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL3200450 | 0.85 | THRB (0.32) | LMNATHRB | |
| SCHEMBL31082798 | 0.81 | — | — | |
| SCHEMBL8618377 | 0.80 | LMNA (0.45) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL8613630 | 0.80 | LMNA (0.45) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL31083404 | 0.77 | — | — | |
| SCHEMBL1779065 | 0.76 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194848-B1 | TERTIARY PERFLUOROALKOXIDES AS SURFACTANTS IN PTFE DISPERSION POLYMERIZATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-18 | — | — | EP | claimed |
| US-4564661-A | Tertiary perfluoroalkoxides as surfactants in PTFE dispersion polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-14 | — | — | US | claimed |
| US-20060252840-A1 | Fluorinated compounds | SONUS PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | US | disclosed |
| US-7091374-B1 | Useful as oxygen carriers and surfactants | SONUS PHARMACEUTICALS, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-6864386-B1 | Fluorinated compounds | SONUS PHARMACEUTICALS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| EP-0194848-B1 | TERTIARY PERFLUOROALKOXIDES AS SURFACTANTS IN PTFE DISPERSION POLYMERIZATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0194848-A1 | Tertiary perfluoroalkoxides as surfactants in PTFE dispersion polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-17 | — | — | EP | disclosed |
| US-4564661-A | Tertiary perfluoroalkoxides as surfactants in PTFE dispersion polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-14 | — | — | US | disclosed |