SCHEMBL8613630

SCHEMBL8613630

OC(F)(F)C(O)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
THRB P10828 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618377 1.00 LMNA (0.45) LMNATHRBCA1CA2MMP1
SCHEMBL8612978 0.90 THRB (0.30) LMNATHRB
SCHEMBL9712157 0.88 LMNA (0.45) LMNATHRBCA1CA2MMP1
SCHEMBL15789011 0.84 LMNA (0.47) LMNATHRBCA1CA2MMP1
SCHEMBL5865458 0.80 LMNA (0.50) LMNATHRBCA1CA2MMP1
SCHEMBL10593459 0.80 LMNA (0.50) LMNATHRBCA1CA2MMP1
SCHEMBL9228374 0.76 LMNA (0.44) LMNATHRBCA1CA2MMP1
SCHEMBL6236464 0.76 LMNA (0.44) LMNATHRBCA1CA2MMP1
SCHEMBL6443127 0.76 LMNA (0.44) LMNATHRBCA1CA2MMP1
SCHEMBL50596 0.76 LMNA (0.44) LMNATHRBCA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed