Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450966 | 0.84 | MAOA (0.70) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL29413779 | 0.82 | MAOA (0.58) | MAOAMAOBMEN1KMT2ATSHR | |
| SCHEMBL88261 | 0.82 | MAOA (0.58) | MAOAMAOBMEN1KMT2ATSHR | |
| SCHEMBL31545095 | 0.82 | MEN1 (0.48) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL3420122 | 0.79 | ATM (0.44) | MAOAMAOBMEN1KMT2ATSHR | |
| SCHEMBL7506342 | 0.78 | ATM (0.53) | MEN1KMT2AALDH1A1HSD17B10ESR2 | |
| SCHEMBL27519942 | 0.78 | MEN1 (0.45) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL14301526 | 0.78 | MEN1 (0.45) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL19851151 | 0.76 | MEN1 (0.64) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL24148895 | 0.76 | MEN1 (0.59) | MEN1KMT2AALDH1A1HSD17B10ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038037-B2 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2006-05-02 | — | — | US | claimed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | claimed |
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | claimed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | claimed |
| US-7038037-B2 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050106598-A1 | Novel peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2005-05-19 | — | — | US | disclosed |
| US-6878805-B2 | Peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2005-04-12 | — | — | US | disclosed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2004016274-A3 | NOVEL PEPTIDE-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004016274-A2 | NOVEL PEPTIDE-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2004-02-26 | — | — | WO | disclosed |
| US-20040034191-A1 | Novel peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | disclosed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | PCNA, MSN, SSBP1 | MAOA 1808/4885MAOB 1494/4885MEN1 2611/4885 |
| US-20040034191-A1 | Novel peptide-conjugated oligomeric compounds | IAPP, NGLY1, TAP1 | MAOA 4683/4885MAOB 4633/4885MEN1 1332/4885 |
| US-20050106598-A1 | Novel peptide-conjugated oligomeric compounds | IAPP, NGLY1, TAP1 | MAOA 4683/4885MAOB 4633/4885MEN1 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.