Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413779 | 0.82 | MAOA (0.58) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL88261 | 0.82 | MAOA (0.58) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL5865591 | 0.79 | MAOA (0.47) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL6566874 | 0.72 | L3MBTL1 (0.50) | ATMCYP2C9MEN1KMT2AUSP2 | |
| SCHEMBL16450352 | 0.71 | CYP3A4 (0.43) | MEN1KMT2AUSP2NR3C1TP53 | |
| SCHEMBL7219661 | 0.71 | ATM (0.47) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL3374471 | 0.71 | ATM (0.47) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL7880558 | 0.71 | ATM (0.47) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL2277251 | 0.69 | MAOB (0.50) | MAOAMAOBSMN1; SMN2NPSR1MAPT | |
| SCHEMBL1461768 | 0.69 | MAOA (0.44) | ATMMAOAMAOBCYP2C9HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038037-B2 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2006-05-02 | — | — | US | claimed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | claimed |
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | claimed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | claimed |
| EP-2226637-A1 | Cross-linking agents on solid medium | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-09-08 | — | — | EP | disclosed |
| US-7038037-B2 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050106598-A1 | Novel peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2005-05-19 | — | — | US | disclosed |
| US-6878805-B2 | Peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2005-04-12 | — | — | US | disclosed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2004016274-A3 | NOVEL PEPTIDE-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004016274-A2 | NOVEL PEPTIDE-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2004-02-26 | — | — | WO | disclosed |
| US-20040034191-A1 | Novel peptide-conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | ISIS PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | disclosed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006203-A1 | Method for sequential support-bound synthesis of conjugated oligomeric compounds | PCNA, MSN, SSBP1 | ATM 3803/4885MAOA 1808/4885MAOB 1494/4885 |
| US-20040034191-A1 | Novel peptide-conjugated oligomeric compounds | IAPP, NGLY1, TAP1 | ATM 4743/4885MAOA 4683/4885MAOB 4633/4885 |
| US-20050106598-A1 | Novel peptide-conjugated oligomeric compounds | IAPP, NGLY1, TAP1 | ATM 4743/4885MAOA 4683/4885MAOB 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.