Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865765 | 1.00 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8743683 | 0.88 | CA12 (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29483451 | 0.87 | MAPT (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL28724766 | 0.87 | MAPT (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL11065106 | 0.84 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20365632 | 0.84 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3977494 | 0.84 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL11313163 | 0.81 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL29483453 | 0.79 | CES2 (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL28519063 | 0.79 | CES2 (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041419-B2 | Charge transfer compounds, charge generating compound and polymer | MINOLTA CO., LTD. (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20030087171-A1 | Organic photoreceptor unit | MINOLTA CO., LTD. (JP) | 2003-05-08 | — | — | US | disclosed |