Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494913 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TDP1APPADAMTS4PTPN1 | |
| SCHEMBL11842494 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1ADAMTS4PTPN1PTPRC | |
| SCHEMBL13291829 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TDP1ADAMTS4PTPN1PTPRC | |
| SCHEMBL2965327 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TDP1ADAMTS4CYP3A4HIF1A | |
| SCHEMBL11757234 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TDP1ADAMTS4PTPN1CYP1A2 | |
| SCHEMBL7785924 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TDP1ADAMTS4PTPN1PTPRC | |
| SCHEMBL6723797 | 0.74 | CYP1A2 (0.50) | ALDH1A1TDP1APPPTPRCS100A4 | |
| SCHEMBL3555427 | 0.74 | ALDH1A1 (0.71) | ALDH1A1TDP1ADAMTS4PTPN1PTPRC | |
| SCHEMBL1814058 | 0.74 | ALDH1A1 (0.64) | ALDH1A1TDP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL2331432 | 0.74 | TDP1 (0.71) | ALDH1A1TDP1ADAMTS4PTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087789-B2 | Methods for nucleophilic fluoromethylation | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-08-08 | — | — | US | claimed |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | SOUTHERN CALIFORNIA, UNIVERSITY OF | 2004-11-18 | — | — | US | claimed |
| WO-2004063129-A2 | METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-07-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | PHF2, HAO2, GSTM2 | ALDH1A1 1240/4885TDP1 3687/4885APP 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.