Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381889 | 0.77 | HTR2C (0.52) | HTR2CHTR2BHTTNPSR1ADRA1D | |
| SCHEMBL29644871 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTTNPSR1MAPT | |
| SCHEMBL1748567 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTTNPSR1MAPT | |
| SCHEMBL11556099 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTTNPSR1ADRA1D | |
| SCHEMBL1536905 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTTNPSR1ADRA1D | |
| SCHEMBL6433379 | 0.74 | HTR2C (0.49) | HTR2CHTR2BHTTNPSR1ADRA1D | |
| Ethane SCHEMBL10720474 | 0.72 | HTR2C (0.47) | HTR2CHTR2BHTTNPSR1MAPT | |
| SCHEMBL7189873 | 0.72 | HTR2C (0.41) | HTR2CHTR2BHTTNPSR1 | |
| SCHEMBL12640789 | 0.71 | HTR2C (0.46) | HTR2CHTR2BHTTNPSR1ADRA1D | |
| SCHEMBL8871056 | 0.71 | HTR2C (0.46) | HTR2CHTR2BHTTNPSR1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599743-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | Heuris Pharma LLC (US) | 2005-11-30 | — | — | EP | claimed |
| US-20040211917-A1 | Three-dimensional dosimeter for penetrating radiation and method of use | HEURIS PHARMA, LLC | 2004-10-28 | — | — | US | claimed |
| WO-2004079393-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | HEURIS PHARMA LLC (US) | 2004-09-16 | — | — | WO | claimed |
| WO-2023211667-A1 | MULTILAYER RADIOCHROMIC STRUCTURES AND USES THEREOF | ISP INVESTMENTS LLC (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-2546679-A1 | \"Three-dimensional dosimeter for penetrating radiation and method of use\ | Heuris Pharma LLC (US) | 2013-01-16 | — | — | EP | disclosed |
| CN-1926108-B | Non-nucleotide reverse transcriptase inhibitors | MEDIVIR AB | 2010-06-09 | — | — | CN | disclosed |
| CN-1926108-A | Non-nucleotide reverse transcriptase inhibitors | MEDIVIR AB (SE) | 2007-03-07 | — | — | CN | disclosed |
| US-7098463-B2 | Three-dimensional dosimeter for penetrating radiation and method of use | HEURIS PHARMA, LLC (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1599743-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | Heuris Pharma LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20040211917-A1 | Three-dimensional dosimeter for penetrating radiation and method of use | HEURIS PHARMA, LLC | 2004-10-28 | — | — | US | disclosed |
| WO-2004079393-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | HEURIS PHARMA LLC (US) | 2004-09-16 | — | — | WO | disclosed |