Sugi Predict

Sugi Predict / Compounds / 2,4-Dinitrophenol

2,4-Dinitrophenol

2,4-Dinitrophenol

SCHEMBL5866337

O=[N+]([O-])c1ccc(O)c([N+](=O)[O-])c1.O=[N+]([O-])c1cccc([N+](=O)[O-])c1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 5/20 0.79
▸ ALDH1A1 P00352 4/20 0.79
▸ MAPK1 P28482 3/20 0.79
▸ TSHR P16473 3/20 0.79
▸ HPGD P15428 2/20 0.79
▸ TP53 P04637 1/20 0.79
▸ SMN1; SMN2 Q16637 1/20 0.79
▸ ALOX15 P16050 3/20 0.53
▸ HSD17B10 Q99714 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ HIF1A Q16665 2/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ TTR P02766 1/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ RECQL P46063 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trinitrophenol SCHEMBL23697948 0.89 GPR35 (0.85) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL27905661 0.89 ALDH1A1 (0.85) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL1517938 0.89 GPR35 (1.00) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL77643 0.89 GPR35 (1.00) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL29361027 0.89 GPR35 (1.00) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL4427609 0.87 GPR35 (0.96) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL16553313 0.87 GPR35 (0.96) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL10714787 0.87 GPR35 (0.96) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL3499025 0.87 GPR35 (0.96) GPR35ALDH1A1MAPK1TSHRHPGD
2,4-Dinitrophenol SCHEMBL1525711 0.87 GPR35 (0.96) GPR35ALDH1A1MAPK1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7071105-B2 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION (US) 2006-07-04 — — US disclosed
US-20040152309-A1 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION 2004-08-05 — — US disclosed
EP-0283315-A1 Method for recovery of polymerization inhibitor NIPPON STEEL CHEMICAL CO., LTD. (JP) 1988-09-21 — — EP disclosed