⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL1011517 | 0.97 | EPHX1 (0.35) | — | |
| Methane SCHEMBL1010580 | 0.97 | — | — | |
| SCHEMBL10957633 | 0.90 | — | — | |
| SCHEMBL5866464 | 0.84 | — | — | |
| Methane SCHEMBL1650698 | 0.82 | OPRM1 (0.34) | — | |
| Ethane SCHEMBL1650765 | 0.82 | OPRM1 (0.34) | — | |
| SCHEMBL5866459 | 0.82 | OPRM1 (0.36) | — | |
| SCHEMBL5759115 | 0.77 | — | — | |
| SCHEMBL870599 | 0.77 | — | — | |
| Ethane SCHEMBL1010902 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3134396-B1 | AMINO PYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| WO-2019149228-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | 成都安诺晨创医药科技有限公司 | 2019-08-08 | — | — | WO | disclosed |
| US-9850236-B2 | Trifluoromethyl alcohols as modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2017-12-26 | — | — | US | disclosed |
| US-20170327492-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-16 | — | — | US | disclosed |
| WO-2016082930-A9 | SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II | Grünenthal GmbH (DE) | 2016-11-24 | — | — | WO | disclosed |
| WO-2016082930-A1 | SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II | Grünenthal GmbH (DE) | 2016-06-02 | — | — | WO | disclosed |
| US-20160122336-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (US) | 2016-05-05 | — | — | US | disclosed |
| US-7048368-B2 | Ink-jet image forming method | KONICA CORPORATION (JP) | 2006-05-23 | — | — | US | disclosed |
| US-7014310-B2 | Inkjet image forming method and inkjet image forming system | KONICA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| US-20040036753-A1 | Ink-jet image forming method | KONICA CORPORATION (JP) | 2004-02-26 | — | — | US | disclosed |
| US-20030202079-A1 | Inkjet image forming method and inkjet image forming system | KONICA CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |