Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.60 |
| ▸ | FLT1 | P17948 | 9/20 | 0.60 |
| ▸ | ABL1 | P00519 | 7/20 | 0.60 |
| ▸ | BCR | P11274 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866803 | 0.88 | ABL1 (0.49) | FGFR1FLT1ABL1CHEK1CDK4 | |
| SCHEMBL5866718 | 0.86 | ABL1 (0.47) | FGFR1FLT1ABL1BCRCDK4 | |
| SCHEMBL5866777 | 0.85 | FGFR1 (0.46) | FGFR1FLT1ABL1CHEK1CDK4 | |
| SCHEMBL5866701 | 0.85 | FGFR1 (0.60) | FGFR1FLT1ABL1BCR | |
| SCHEMBL3542579 | 0.79 | FGFR1 (0.46) | FGFR1FLT1ABL1BCRCHEK1 | |
| SCHEMBL3536239 | 0.79 | FGFR1 (0.82) | FGFR1FLT1ABL1BCR | |
| SCHEMBL3541264 | 0.79 | FGFR1 (0.74) | FGFR1FLT1ABL1BCRCDK4 | |
| SCHEMBL3542676 | 0.78 | FGFR1 (0.48) | FGFR1FLT1ABL1CHEK1CDK2 | |
| SCHEMBL5866910 | 0.77 | FGFR1 (0.42) | FGFR1FLT1ABL1CHEK1CDK4 | |
| SCHEMBL3540813 | 0.76 | FGFR1 (0.73) | FGFR1FLT1ABL1BCRCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |