Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 13/20 | 0.60 |
| ▸ | FLT1 | P17948 | 10/20 | 0.60 |
| ▸ | ABL1 | P00519 | 7/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866718 | 0.89 | ABL1 (0.47) | FGFR1FLT1ABL1BCRUSP30 | |
| SCHEMBL5866685 | 0.88 | FGFR1 (0.44) | FGFR1FLT1ABL1PDPK1 | |
| SCHEMBL5866660 | 0.85 | FGFR1 (0.60) | FGFR1FLT1ABL1BCR | |
| SCHEMBL3541772 | 0.79 | FGFR1 (0.74) | FGFR1FLT1ABL1BCR | |
| SCHEMBL5866910 | 0.78 | FGFR1 (0.42) | FGFR1FLT1ABL1PDPK1 | |
| SCHEMBL3536775 | 0.78 | FGFR1 (0.45) | FGFR1FLT1ABL1BCRPDPK1 | |
| SCHEMBL3542676 | 0.77 | FGFR1 (0.48) | FGFR1FLT1ABL1PDPK1 | |
| SCHEMBL5866690 | 0.76 | FGFR1 (0.40) | FGFR1FLT1ABL1PDPK1 | |
| SCHEMBL3534254 | 0.76 | FGFR1 (0.43) | FGFR1FLT1ABL1BCRPDPK1 | |
| SCHEMBL3538199 | 0.76 | FGFR1 (0.42) | FGFR1FLT1ABL1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |