Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866960 | 0.88 | KMT2A (0.48) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL5751689 | 0.86 | CYP3A4 (0.43) | IKBKETBK1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5749987 | 0.86 | ALDH1A1 (0.51) | KMT2AMEN1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5867000 | 0.83 | FGFR1 (0.47) | CYP2C9CYP2C19CYP3A4CYP2A6FGFR1 | |
| SCHEMBL5866915 | 0.83 | FGFR1 (0.47) | IKBKETBK1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5750702 | 0.79 | GAA (0.43) | KMT2AMEN1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5746964 | 0.79 | IMPDH2 (0.47) | KMT2AMEN1TAAR1ROCK1CYP2C9 | |
| SCHEMBL5751620 | 0.78 | ADORA3 (0.47) | KMT2AMEN1TAAR1ROCK1NPC1 | |
| SCHEMBL5750679 | 0.77 | KMT2A (0.45) | KMT2AMEN1TAAR1ROCK1IKBKE | |
| SCHEMBL5751374 | 0.77 | IMPDH2 (0.48) | KMT2AMEN1TAAR1ROCK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005434-B2 | Compounds and uses thereof | SB CORPORATION (US) | 2006-02-28 | — | — | US | disclosed |
| US-20040048888-A1 | Novel compounds and uses thereof | SMITHKLINE BEECHAM CORPORATION | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048888-A1 | Novel compounds and uses thereof | TEK, TIE1, KDR | KMT2A 1785/4885MEN1 1650/4885TAAR1 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.