Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SCN2B | O60939 | 1/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443628 | 0.90 | LMNA (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6211761 | 0.89 | LMNA (0.57) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5868709 | 0.85 | LMNA (0.68) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8137475 | 0.85 | ALDH1A1 (0.61) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10474316 | 0.84 | MAPK8 (0.54) | LMNAMEN1KMT2ARORCCAPN1 | |
| SCHEMBL9443548 | 0.83 | KDM4E (0.79) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5868704 | 0.83 | LMNA (0.80) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9869652 | 0.82 | ALDH1A1 (0.63) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10757460 | 0.82 | CAPN1 (0.60) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9046544 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098219-B2 | Quinolone derivatives | WOCKHART LIMITED (IN) | 2006-08-29 | — | — | US | disclosed |
| US-20020177559-A1 | Quinolone derivatives | WOCKHARDT LIMITED | 2002-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177559-A1 | Quinolone derivatives | ABCB11, ABCB1, ABCG2 | LMNA 1664/4885MEN1 2581/4885KMT2A 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.