Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624829 | 1.00 | LOXL2 (0.39) | LOXL2TP53MAOBBCHECALM1 | |
| SCHEMBL14631643 | 1.00 | LOXL2 (0.39) | LOXL2TP53MAOBBCHECALM1 | |
| SCHEMBL15944116 | 0.78 | TP53 (0.41) | TP53MAOBBCHECALM1ALDH1A1 | |
| SCHEMBL29094830 | 0.78 | TP53 (0.41) | TP53MAOBBCHECALM1ALDH1A1 | |
| SCHEMBL29094779 | 0.77 | TAAR1 (0.38) | TP53CYP2A6SMN1; SMN2TAAR1TSHR | |
| SCHEMBL27676164 | 0.76 | LOXL2 (0.42) | LOXL2TP53MAOBCALM1CYP2A6 | |
| SCHEMBL268060 | 0.76 | BCHE (0.41) | MAOBBCHECALM1ALDH1A1TSHR | |
| SCHEMBL20562244 | 0.76 | BCHE (0.41) | MAOBBCHECALM1ALDH1A1TSHR | |
| SCHEMBL27507506 | 0.76 | MAOB (0.46) | LOXL2TP53MAOBBCHECALM1 | |
| SCHEMBL76727 | 0.76 | BCHE (0.41) | MAOBBCHECALM1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7066990-B2 | Ink jet ink and recording material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-27 | — | — | US | claimed |
| EP-1587887-A1 | INK-JET INK AND RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2005-10-26 | — | — | EP | claimed |
| US-20040170779-A1 | Ink jet ink and recording material | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-02 | — | — | US | claimed |
| WO-2004067652-A1 | INK-JET INK AND RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-12 | — | — | WO | claimed |
| US-9676715-B2 | Bis-indolic derivatives, a process for preparing the same and their uses as a drug | UNIVERSITE JOSEPH FOURIER (FR) | 2017-06-13 | — | — | US | disclosed |
| US-20140309272-A1 | BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG | UNIVERSITE JOSEPH FOURIER (FR) | 2014-10-16 | — | — | US | disclosed |
| EP-2548865-B1 | Novel bis-indolic derivatives, their uses in particular as antibacterials | UNIV JOSEPH FOURIER (FR) | 2014-03-05 | — | — | EP | disclosed |
| EP-2548864-B1 | NOVEL BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG | UNIV JOSEPH FOURIER (FR) | 2014-02-19 | — | — | EP | disclosed |
| EP-2548865-A1 | Novel bis-indolic derivatives, their uses in particular as antibacterials | Université Joseph Fourier (FR) | 2013-01-23 | — | — | EP | disclosed |
| EP-2548864-A1 | NOVEL BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG | Université Joseph Fourier (FR) | 2013-01-23 | — | — | EP | disclosed |
| CN-100354262-C | Sterically hindered amine compound | CIBA SC HOLDING AG (CH) | 2007-12-12 | — | — | CN | disclosed |
| US-7066990-B2 | Ink jet ink and recording material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20040170779-A1 | Ink jet ink and recording material | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-02 | — | — | US | disclosed |
| WO-2004067652-A1 | INK-JET INK AND RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-12 | — | — | WO | disclosed |
| CN-1120165-C | Block oligomers containing 2,2,6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | CIBA SC HOLDING AG (CH) | 2003-09-03 | — | — | CN | disclosed |
| CN-1106398-C | Block oligomers containing 1-hydrocarbyloxy-2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | CIBA SC HOLDING AG (CH) | 2003-04-23 | — | — | CN | disclosed |
| CN-1257863-A | Sterically hindered amine compound | CIBA SC HOLDING AG (CH) | 2000-06-28 | — | — | CN | disclosed |
| CN-1257495-A | Block oligomers containing 1-hydrocarbyloxy-2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | CIBA SC HOLDING AG (CH) | 2000-06-21 | — | — | CN | disclosed |
| CN-1257492-A | Block oligomers containing 1-hydrocarbyloxy-2, 2,6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | CIBA SC HOLDING AG (CH) | 2000-06-21 | — | — | CN | disclosed |
| CN-1165138-A | Block oligomers containing 2, 2, 6, 6-tetramethyl-4-piperidyl groups as stabilizers for organic materials | CIBA GEIGY AG (CH) | 1997-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309272-A1 | BIS-INDOLIC DERIVATIVES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG | IDO1, ITPA, IDO2 | LOXL2 4456/4885TP53 2601/4885MAOB 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.