SCHEMBL268060

SCHEMBL268060

[O-]/[N+](=C\c1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
G6PD P11413 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
FBP1 P09467 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
RECQL P46063 1/20 0.37
HAO1 Q9UJM8 1/20 0.37
MAOB P27338 1/20 0.36
CALM1 P0DP23 1/20 0.35
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20562244 1.00 BCHE (0.41) BCHEG6PDPOLBGAATDP1
SCHEMBL76727 1.00 BCHE (0.41) BCHEG6PDPOLBGAATDP1
SCHEMBL29094776 0.87 G6PD (0.51) BCHEG6PDGAAMEN1KMT2A
SCHEMBL29094803 0.87 HTT (0.42) BCHEPOLBFBP1NPC1RAB9A
SCHEMBL29094784 0.87 ALDH1A1 (0.56) BCHEFBP1NPC1RAB9AALDH1A1
SCHEMBL29094816 0.87 G6PD (0.51) BCHEG6PDFBP1NPC1ALDH1A1
SCHEMBL28858924 0.87 FNTA (0.43) G6PD
SCHEMBL18308936 0.87 FNTA (0.43) G6PD
SCHEMBL29094785 0.84 MAPT (0.50) BCHEPOLBMEN1KMT2ANPC1
SCHEMBL29094804 0.82 FBP1 (0.45) BCHETDP1FBP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3371148-B1 USE AND PREPARATION OF REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS DISPOLTEC B V (NL) 2021-05-05 EP disclosed
US-10947325-B2 Regulators for controlling linear and pseudo-ring expansion polymerization of vinyl monomers DISPOLTEC B.V. (NL) 2021-03-16 US disclosed
US-20180334516-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS DISPOLTEC B.V. (NL) 2018-11-22 US disclosed
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 EP disclosed
US-8133834-B2 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-13 US disclosed
US-20100069670-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-18 US disclosed
EP-1348692-B1 Process for the preparation of amine oxides COUNCIL SCIENT IND RES (IN) 2008-12-31 EP disclosed
US-20060229471-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-10-12 US disclosed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 EP disclosed
EP-1412335-A4 ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS CALIFORNIA INST OF TECHN (US) 2004-11-17 EP disclosed
US-20030109718-A1 Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-06-12 US disclosed
WO-2003002491-A2 ENANTIOSELECTIVE TRANSFORMATION OF α, β-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-01-09 WO disclosed
US-6455735-B1 REACTING A TERTIARY OR SECONDARY AMINE WITH HYDROGEN PEROXIDE IN PRESENCE OF A RECYCLABLE HETEROGENEOUS LAYERED DOUBLE HYDROXIDE EXCHANGED WITH ONE OF THE ANIONS OF TRANSITION METAL OXIDES AS A CATALYST IN A SOLVENT COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-24 US disclosed
US-20020095055-A1 Process for the preparation of amine oxides COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-07-18 US disclosed
EP-1213280-A2 A process for the preparation of amine oxides Council of Scientific and Industrial Research (IN) 2002-06-12 EP disclosed
EP-1209148-A1 Process for the preparation of amine oxides Council of Scientific and Industrial Research (IN) 2002-05-29 EP disclosed
US-6323367-B1 REACTING TERTIARY OR SECONDARY AMINE WITH HYDROGEN PEROXIDE AS AN OXIDANT IN PRESENCE OF A RECYCLABLE HETEROGENEOUS LAYERED DOUBLE HYDROXIDE EXCHANGED WITH TRANSITION METAL OXIDES AS A CATALYST IN AN ORGANIC SOLVEN, STIRRING, FILTRATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2001-11-27 US disclosed
US-5137951-A For organic materials subject to oxidative, thermal or actinic degradation CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
US-5077329-A Oxidation, heat, actinic radiation stabilizers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5037867-A To stabilize polymer against oxidation, thermal and actinic radiation degradation CIBA-GEIGY CORPORATION (US) 1991-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109718-A1 Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts ALDH1A1, GAR1, ALDH1B1 BCHE 3595/4885G6PD 2633/4885POLB 752/4885
US-20180334516-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS ORC3, RPS27L, OXGR1 BCHE 4412/4885G6PD 1302/4885POLB 1997/4885
US-10947325-B2 Regulators for controlling linear and pseudo-ring expansion polymerization of vinyl monomers ORC3, RPS27L, OXGR1 BCHE 4412/4885G6PD 1302/4885POLB 1997/4885
US-20100069670-A1 Oxidation catalyst PPOX, SOD1, HAO2 BCHE 1176/4885G6PD 198/4885POLB 549/4885
US-20060229471-A1 Oxidation catalyst PPOX, SOD1, HAO2 BCHE 1176/4885G6PD 198/4885POLB 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.