Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646746 | 0.80 | HCAR2 (0.41) | HCAR2KDM4EHCAR3CYP2C19HSD17B10 | |
| SCHEMBL6469858 | 0.77 | HTT (0.38) | HCAR2KDM4ECYP2C19HSD17B10PIN1 | |
| SCHEMBL5870382 | 0.77 | ALDH1A1 (0.39) | KDM4ECYP2C19 | |
| Formamide SCHEMBL5870611 | 0.75 | HCAR2 (0.39) | HCAR2HCAR3CYP2C19HSD17B10PIN1 | |
| SCHEMBL28211381 | 0.68 | HCAR2 (0.45) | HCAR2HCAR3HAO1 | |
| SCHEMBL7426789 | 0.67 | HCAR2 (0.44) | HCAR2KDM4EHCAR3CYP2C19HSD17B10 | |
| SCHEMBL5870589 | 0.67 | CYP2C19 (0.65) | HCAR2KDM4EHCAR3CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL5869997 | 0.66 | CYP2C19 (0.62) | HCAR2KDM4EHCAR3CYP2C19HSD17B10 | |
| SCHEMBL651 | 0.66 | PIN1 (0.42) | HCAR2CYP2C19KDM5AKDM5BPIN1 | |
| SCHEMBL17224170 | 0.64 | HCAR2 (0.55) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078528-B2 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050004370-A1 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004370-A1 | Biimidazole diamide anion binding agents | ABCG2, BRI3BP, SLCO1B3 | HCAR2 3094/4885KDM4E 4206/4885HCAR3 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.