Pivalate

Pivalate

SCHEMBL5870604

CC(C)(C)C(=O)O.CN(C)Cc1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
TSHR P16473 1/20 0.68
RIPK1 Q13546 2/20 0.54
TAAR1 Q96RJ0 1/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
RECQL P46063 1/20 0.50
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 1/20 0.47
LMNA P02545 1/20 0.47
AOC3 Q16853 1/20 0.47
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL4671806 0.87 ALDH1A1 (0.81) ALDH1A1TSHRRIPK1TAAR1NPC1
Bicarbonate SCHEMBL14811027 0.87 ALDH1A1 (0.81) ALDH1A1TSHRRIPK1TAAR1NPC1
Trifluoroacetic Acid SCHEMBL27585620 0.86 ALDH1A1 (0.65) ALDH1A1TSHRRIPK1TAAR1NPC1
Oxalic Acid SCHEMBL11785204 0.85 ALDH1A1 (0.77) ALDH1A1TSHRRIPK1TAAR1NPC1
Acetic Acid SCHEMBL3621604 0.85 ALDH1A1 (0.77) ALDH1A1TSHRRIPK1TAAR1NPC1
Carbamic Acid SCHEMBL30426064 0.83 ALDH1A1 (0.74) ALDH1A1TSHRRIPK1TAAR1NPC1
Urea SCHEMBL28073648 0.83 ALDH1A1 (0.74) ALDH1A1TSHRRIPK1TAAR1NPC1
Chloromethane SCHEMBL28157121 0.83 TSHR (0.90) ALDH1A1TSHRTAAR1NPC1RAB9A
Methyl Alcohol SCHEMBL2647148 0.83 TSHR (0.90) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL24735547 0.82 TSHR (1.00) ALDH1A1TSHRTAAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US disclosed
US-20030187178-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2003-10-02 US disclosed
US-6613863-B2 Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts DEGUSSA AG (DE) 2003-09-02 US disclosed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US disclosed