Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29752049 | 0.83 | CYP3A4 (0.60) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| SCHEMBL456953 | 0.83 | CYP3A4 (0.60) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL10585448 | 0.82 | PDE10A (0.63) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| SCHEMBL9763245 | 0.81 | PDE10A (0.52) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL27284 | 0.81 | — | — | |
| 2,4-Diaminophenol SCHEMBL1884352 | 0.79 | ALDH1A1 (0.54) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL11222476 | 0.79 | ALDH1A1 (0.54) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL456211 | 0.79 | ALDH1A1 (0.54) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL7221197 | 0.79 | ALDH1A1 (0.54) | PDE10ACASP1TSHRALDH1A1ALOX15 | |
| 2,4-Diaminophenol SCHEMBL30192203 | 0.79 | ALDH1A1 (0.54) | PDE10ACASP1TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122062-B2 | Hair dye composition | SHISEIDO CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20040103488-A1 | Hair dye composition | SHISEIDO CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040103488-A1 | Hair dye composition | SMURF1, ALKBH3, ALK | PDE10A 4135/4885CASP1 1531/4885TSHR 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.