⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3960568 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL3939821 | 0.98 | — | — | |
| Phosphoric Acid SCHEMBL6547515 | 0.90 | FDPS (0.56) | — | |
| SCHEMBL735969 | 0.86 | — | — | |
| SCHEMBL8671012 | 0.85 | FDPS (0.47) | — | |
| SCHEMBL2089915 | 0.85 | FDPS (0.42) | — | |
| SCHEMBL9256794 | 0.83 | FDPS (0.41) | — | |
| SCHEMBL7275156 | 0.83 | FDPS (0.41) | — | |
| SCHEMBL167744 | 0.80 | — | — | |
| SCHEMBL8381065 | 0.80 | COPS5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116286623-A | Metabolic markers for screening young and senescent mesenchymal stem cell-derived exosomes and screening method | 中国医学科学院基础医学研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-105348215-B | A kind of thiazole compound with beans Flavor odor characteristic and preparation method thereof | 波顿（上海）生物技术有限公司 | 2018-01-02 | — | — | CN | claimed |
| CN-106433973-A | Preparation method of perfume composition | 东莞市联洲知识产权运营管理有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-102584740-B | Synthesis method for 4-methyl-5-(2-ethoxyl)-thiazole | TENGZHOU WUTONG PERFUME CO LTD | 2013-11-27 | — | — | CN | claimed |
| WO-2013085954-A1 | SUBSTITUTED PIPERIDINYL-CARBOXAMIDE DERIVATIVES USEFUL AS SCD 1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-06-13 | — | — | WO | claimed |
| CN-102584740-A | Synthesis method for 4-methyl-5-(2-ethoxyl)-thiazole | TENGZHOU WUTONG PERFUME CO LTD | 2012-07-18 | — | — | CN | claimed |
| US-8143408-B2 | N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | claimed |
| US-20100137322-A1 | NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | claimed |
| US-20100056494-A1 | PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES | IRM LLC (BM) | 2010-03-04 | — | — | US | claimed |
| EP-2158198-A2 | NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008094737-A2 | PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES | IRM LLC (BM) | 2008-08-07 | — | — | WO | claimed |
| EP-1746888-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2007-01-31 | — | — | EP | claimed |
| CN-1271188-C | Perfume compositions | ZHOU JINGLONG (CN) | 2006-08-23 | — | — | CN | claimed |
| WO-2005112640-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2005-12-01 | — | — | WO | claimed |
| CN-1544594-A | Perfume compositions | 周静龙 | 2004-11-10 | — | — | CN | claimed |
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | claimed |
| CN-1051546-C | Novel 1,1-bis (heteroazolyl) alkane derivatives and their use as neuroprotective agents | ASTRA AB (SE) | 2000-04-19 | — | — | CN | claimed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | claimed |
| CN-1150426-A | Novel 1,1-bis (heteroazolyl) alkane derivatives and their use as neuroprotective agents | ASTRA AB (SE) | 1997-05-21 | — | — | CN | claimed |
| EP-0516069-A1 | Leukotriene B4 antagonist | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-12-02 | — | — | EP | claimed |