SCHEMBL9158519

SCHEMBL9158519

CCCCCCCCNC(=O)N1CCCCCC1=O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
NAMPT P43490 2/20 0.45
ASAH1 Q13510 1/20 0.45
NAAA Q02083 1/20 0.43
EPHX1 P07099 6/20 0.42
EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16381786 1.00 KDM4E (0.45) KDM4ENAMPTASAH1NAAAEPHX1
SCHEMBL5492822 1.00 KDM4E (0.45) KDM4ENAMPTASAH1NAAAEPHX1
SCHEMBL16151989 0.99 KDM4E (0.43) KDM4ENAMPTASAH1NAAAEPHX1
SCHEMBL5871771 0.94 NAMPT (0.47) NAMPTASAH1EPHX1
SCHEMBL11816203 0.94 HTT (0.44)
SCHEMBL16436869 0.93 HTT (0.45)
SCHEMBL5019491 0.93 LMNA (0.44) KDM4ENAMPTASAH1
SCHEMBL18012879 0.93 LMNA (0.44) KDM4ENAMPTASAH1
SCHEMBL1374699 0.93 LMNA (0.44) KDM4ENAMPTASAH1
SCHEMBL16151509 0.91 PAOX (0.43) KDM4ENAMPTASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485928-B1 Process for the preparation of ureidoperoxycarboxylic acids HOECHST AG (DE) 1995-02-01 EP disclosed
US-5235099-A Heating carbamoyllactam with acid catalyst and hydrogen peroxide HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-10 US disclosed
EP-0485928-A2 Process for the preparation of ureidoperoxycarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-20 EP disclosed