Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872356 | 0.72 | IDO1 (0.34) | CES2KDM1AIDO1 | |
| SCHEMBL5872319 | 0.66 | CES2 (0.39) | CES2POLQ | |
| SCHEMBL3962902 | 0.64 | CES2 (0.52) | CES2TSHRMAPK1 | |
| SCHEMBL30721709 | 0.64 | CES2 (0.52) | CES2TSHRMAPK1 | |
| SCHEMBL2699647 | 0.64 | CES2 (0.52) | CES2TSHRALOX5APFEN1IDO1 | |
| SCHEMBL30417923 | 0.64 | CES2 (0.52) | CES2TSHRALOX5APFEN1IDO1 | |
| SCHEMBL6061078 | 0.64 | CES2 (0.56) | CES2TSHRMAPK1 | |
| SCHEMBL11603910 | 0.63 | CES2 (0.43) | CES2TSHRMAPK1IDO1 | |
| SCHEMBL185847 | 0.63 | CES2 (0.50) | CES2TSHRMAPK1 | |
| SCHEMBL6039958 | 0.62 | MPL (0.47) | ALOX5APFEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425318-B1 | ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS | VERSALIS SPA (IT) | 2013-01-16 | — | — | EP | disclosed |
| US-7081505-B2 | Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds | POLIMERI EUROPA S.P.A. (IT) | 2006-07-25 | — | — | US | disclosed |
| US-20040198934-A1 | Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds | POLIMERI EUROPA S.P.A. (IT) | 2004-10-07 | — | — | US | disclosed |
| US-6596891-B1 | Reaction product of fluoroorganic compound and organometallic compound | ENICHEM S.P.A. (IT) | 2003-07-22 | — | — | US | disclosed |
| EP-1013675-B1 | Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins | POLIMERI EUROPA SPA (IT) | 2002-07-31 | — | — | EP | disclosed |
| EP-1013675-A2 | Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins | Enichem S.p.A. (IT) | 2000-06-28 | — | — | EP | disclosed |