SCHEMBL5872334

SCHEMBL5872334

FC(F)(F)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.52
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
PTPN1 P18031 1/20 0.40
TACR1 P25103 2/20 0.38
HRH4 Q9H3N8 1/20 0.37
DUT P33316 2/20 0.35
MAPK1 P28482 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
FABP7 O15540 1/20 0.34
IDO1 P14902 2/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
TDO2 P48775 1/20 0.33
KCNN4 O15554 1/20 0.33
MEN1 O00255 1/20 0.33
S1PR2 O95136 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9078324 0.82 TSHR (0.50) KIF11TSHRALDH1A1PTPN1TACR1
SCHEMBL19469823 0.79 KIF11 (0.46) KIF11TSHRALDH1A1PTPN1TACR1
SCHEMBL6682500 0.79 KIF11 (0.54) KIF11TSHRALDH1A1HRH4DUT
SCHEMBL8571973 0.79 KIF11 (0.54) KIF11TSHRALDH1A1PTPN1HRH4
SCHEMBL8566517 0.78 ALDH1A1 (0.46) KIF11TSHRALDH1A1PTPN1TACR1
SCHEMBL19469860 0.78 KIF11 (0.44) KIF11TSHRALDH1A1PTPN1TACR1
SCHEMBL4544073 0.77 KIF11 (0.52) KIF11TSHRALDH1A1HRH4DUT
SCHEMBL8850056 0.77 KIF11 (0.52) KIF11ALDH1A1HRH4DUTMAPK1
SCHEMBL19474691 0.77 KIF11 (0.43) KIF11TSHRALDH1A1PTPN1TACR1
SCHEMBL19504244 0.77 KIF11 (0.43) KIF11TSHRALDH1A1PTPN1TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP claimed
EP-1425318-B1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS VERSALIS SPA (IT) 2013-01-16 EP disclosed
US-7081505-B2 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2006-07-25 US disclosed
US-20040198934-A1 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2004-10-07 US disclosed
EP-1425318-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS Polimeri Europa S.p.A. (IT) 2004-06-09 EP disclosed
WO-2003010210-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS POLIMERI EUROPA S.P.A. (IT) 2003-02-06 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed