Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571973 | 0.81 | KIF11 (0.54) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL4544073 | 0.79 | KIF11 (0.52) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL5872334 | 0.79 | KIF11 (0.52) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL8850056 | 0.79 | KIF11 (0.52) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL7001869 | 0.77 | KIF11 (0.44) | KIF11KCNN4MAPK1TSHRALDH1A1 | |
| SCHEMBL11275984 | 0.77 | KIF11 (0.74) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL30124105 | 0.76 | KIF11 (0.48) | KIF11HRH4KCNN4DUTMAPK1 | |
| SCHEMBL238217 | 0.73 | KIF11 (0.41) | KIF11KCNN4MAPK1TSHRALDH1A1 | |
| SCHEMBL11248540 | 0.73 | KIF11 (0.41) | KIF11KCNN4MAPK1TSHRALDH1A1 | |
| SCHEMBL9614597 | 0.73 | ALDH1A1 (0.44) | KIF11KCNN4MAPK1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474432-A1 | IMMUNOSTIMULATORY, COVALENTLY LIPIDATED OLIGONUCLEOTIDES | Biomira Inc. (CA) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066649-A1 | IMMUNOSTIMULATORY, COVALENTLY LIPIDATED OLIGONUCLEOTIDES | BIOMIRA INC. (CA) | 2003-08-14 | — | — | WO | disclosed |
| EP-0191659-A1 | Derivatives of adenosine nucleosides, their preparation and their biological use | INSTITUT PASTEUR (FR) | 1986-08-20 | — | — | EP | disclosed |
| EP-0124561-A1 | PROCESS FOR PRODUCING OLIGONUCLEOSIDE PHOSPHONATES. | KOSTER HUBERT | 1984-11-14 | — | — | EP | disclosed |
| WO-1984001778-A1 | PROCESS FOR PRODUCING OLIGONUCLEOSIDE PHOSPHONATES | KOESTER HUBERT (DE) | 1984-05-10 | — | — | WO | disclosed |