Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902156 | 1.00 | LMNA (0.46) | LMNAHTTNPC1S1PR2S1PR4 | |
| SCHEMBL5872086 | 0.95 | LMNA (0.52) | LMNAHTTNPC1S1PR2S1PR4 | |
| SCHEMBL5872237 | 0.87 | PPARG (0.46) | LMNAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6755927 | 0.84 | TDP1 (0.45) | LMNAALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL6756044 | 0.84 | TDP1 (0.45) | LMNAALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL6754918 | 0.84 | TDP1 (0.45) | LMNAALDH1A1MAPTHPGDXBP1 | |
| (Z)-1,2-Diphenylethene SCHEMBL9484423 | 0.82 | EGFR (0.46) | LMNATP53MAPTSMN1; SMN2EGFR | |
| (Z)-1,2-Diphenylethene SCHEMBL9484428 | 0.82 | EGFR (0.46) | LMNATP53MAPTSMN1; SMN2EGFR | |
| SCHEMBL5872294 | 0.81 | PPARG (0.50) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL12513073 | 0.81 | PPARG (0.50) | LMNAHTTNPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559198-B2 | A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of | NOVICKY NICK (CA) | 2003-05-06 | — | — | US | claimed |
| US-20030027886-A1 | Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2003-02-06 | — | — | US | claimed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | claimed |
| EP-0231572-B1 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RES LTD (CA) | 1994-11-02 | — | — | EP | claimed |
| US-4748224-A | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | Devou, Maureen J. (CA) | 1988-05-31 | — | — | US | claimed |
| EP-0231572-A2 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RESEARCH LTD. (CA) | 1987-08-12 | — | — | EP | claimed |
| EP-2349998-B1 | A NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN | BIOPHORE INDIA PHARMACEUTICALS PVT LTD (IN) | 2013-07-17 | — | — | EP | disclosed |
| US-7098282-B2 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK | 2006-08-29 | — | — | US | disclosed |
| US-20050176907-A1 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2005-08-11 | — | — | US | disclosed |
| EP-1455201-A1 | Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof | Novicky, Nick N. (CA) | 2004-09-08 | — | — | EP | disclosed |
| US-6559198-B2 | A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of | NOVICKY NICK (CA) | 2003-05-06 | — | — | US | disclosed |
| US-20030027886-A1 | Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2003-02-06 | — | — | US | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-0231572-B1 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RES LTD (CA) | 1994-11-02 | — | — | EP | disclosed |
| US-5093447-A | Contact lenses | NOVICKY NICK N (CA) | 1992-03-03 | — | — | US | disclosed |
| US-4948855-A | COPOLYMER OF UNSATURATED SILOXANYLALKOXYESTER AND VINYL SILFONE | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1990-08-14 | — | — | US | disclosed |
| US-4861850-A | CONTACT LENSES | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1989-08-29 | — | — | US | disclosed |
| US-4748224-A | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | Devou, Maureen J. (CA) | 1988-05-31 | — | — | US | disclosed |
| US-4743106-A | POLYMER HAVING AN ORGANOSILOXANYLALKOXY ESTER OF (METH)ACRYLIC ACID MONOMER; MACHINING | Devou, Maureen J. (CA) | 1988-05-10 | — | — | US | disclosed |
| EP-0231572-A2 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RESEARCH LTD. (CA) | 1987-08-12 | — | — | EP | disclosed |