Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675669 | 0.86 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL3710148 | 0.82 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL3036340 | 0.82 | SLC6A2 (0.48) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Formic Acid SCHEMBL27642652 | 0.80 | SLC6A2 (0.62) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL12188002 | 0.77 | SLC6A2 (0.70) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL8038687 | 0.77 | SLC6A2 (0.70) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL637250 | 0.77 | SLC6A2 (0.70) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Hydrogen Sulfide SCHEMBL28158135 | 0.76 | SLC6A2 (0.68) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Hydrochloric Acid SCHEMBL3325847 | 0.76 | SLC6A2 (0.71) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Acetic Acid SCHEMBL3036343 | 0.75 | SLC6A2 (0.62) | SLC6A4SLC6A3SLC6A2LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141697-B2 | Process for the preparation of phenethylamine derivatives | SANDOZ AG (CH) | 2006-11-28 | — | — | US | disclosed |
| EP-1343750-B1 | PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| EP-1343750-A1 | PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES | Ciba SC Holding AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-20030114711-A1 | Process for the preparation of phenethylamine derivatives | SANDOZ AG (CH) | 2003-06-19 | — | — | US | disclosed |
| WO-2002050017-A1 | PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114711-A1 | Process for the preparation of phenethylamine derivatives | HNMT, HRH3, HRH1 | SLC6A4 363/4885SLC6A3 273/4885SLC6A2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.