Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714843 | 0.85 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL6707673 | 0.84 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL16675669 | 0.84 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL5872401 | 0.82 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Acetic Acid SCHEMBL3036343 | 0.81 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL3710148 | 0.80 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL12188002 | 0.78 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL8038687 | 0.78 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL637250 | 0.78 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Oxalic Acid SCHEMBL3710175 | 0.78 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035457-A1 | A PROCESS FOR THE MANUFACTURE OF VENLAFAXINE AND INTERMEDIATES THEREOF | AMOLI ORGANICS LTD. (IN) | 2006-04-06 | — | — | WO | claimed |
| US-9604974-B2 | Compounds as modulator of JAK-STAT pathway, methods and applications thereof | UNIVERSITY OF MYSORE (IN) | 2017-03-28 | — | — | US | disclosed |
| US-20160214968-A1 | COMPOUNDS AS MODULATOR OF JAK-STAT PATHWAY, METHODS AND APPLICATIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-07-28 | — | — | US | disclosed |
| US-20100210719-A1 | O-DESMETHYLVENLAFAXINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-08-19 | — | — | US | disclosed |
| WO-2009009665-A2 | O-DESMETHYLVENLAFAXINE | DR. REDDY'S LABORATORIES, LTD. (IN) | 2009-01-15 | — | — | WO | disclosed |
| CN-101245021-A | Process for synthesizing 1-[2-amido-1-(4-methoxy phenyl)ethyl]cyclohexanol acetate | SHANGHAI HUASHI MEDICAL HI TEC (CN) | 2008-08-20 | — | — | CN | disclosed |
| EP-1721889-A1 | Process for the preparation of phenethylamine derivatives | Dishman Pharmaceuticals & Chemicals Ltd. (IN) | 2006-11-15 | — | — | EP | disclosed |
| WO-2006035457-A1 | A PROCESS FOR THE MANUFACTURE OF VENLAFAXINE AND INTERMEDIATES THEREOF | AMOLI ORGANICS LTD. (IN) | 2006-04-06 | — | — | WO | disclosed |
| US-20050033088-A1 | Process for the preparation of phenethylamine derivative, an intermediate of Venlafaxine hydrochloride | DR. REDDY'S LABORATORIES LIMITED | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210719-A1 | O-DESMETHYLVENLAFAXINE | SLC6A4, SLC6A2, CYP2D6 | SLC6A2 2/4885SLC6A4 1/4885SLC6A3 7/4885 |
| US-20160214968-A1 | COMPOUNDS AS MODULATOR OF JAK-STAT PATHWAY, METHODS AND APPLICATIONS THEREOF | STAT3, STAT1, JAK2 | SLC6A2 4791/4885SLC6A4 4636/4885SLC6A3 4618/4885 |
| US-20050033088-A1 | Process for the preparation of phenethylamine derivative, an intermediate of Venlafaxine hydrochloride | COMT, PNMT, MAOA | SLC6A2 4/4885SLC6A4 10/4885SLC6A3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.