SCHEMBL5872439

SCHEMBL5872439

CS(=O)(=O)N(CO)S(C)(=O)=O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176138 0.75 MAPT (0.38) MEN1KMT2A
Hydrochloric Acid SCHEMBL6021767 0.75 TSHR (0.31)
SCHEMBL20173258 0.73
SCHEMBL7567519 0.72 KDM4E (0.36) MEN1KMT2ACHRM2CHRM4CHRM5
SCHEMBL2640947 0.69 SMN1; SMN2 (0.33) MEN1KMT2ACA2
SCHEMBL2359551 0.69 KDM4E (0.33) MEN1KMT2ACHRM2CHRM4CHRM5
SCHEMBL22196960 0.67 CHRM2 (0.31) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL145294 0.65 CHRM2 (0.30) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7127686 0.65 CHRM2 (0.30) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4666266 0.65 CA1 (0.48) KMT2ACHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US disclosed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US disclosed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP disclosed