Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22196960 | 0.86 | CHRM2 (0.31) | KDM4ECYP3A4CA1CHRM2CHRM4 | |
| SCHEMBL145294 | 0.83 | CHRM2 (0.30) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4666266 | 0.83 | CA1 (0.48) | CA1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2731669 | 0.81 | TRPA1 (0.36) | CA1CA12CA2CA14 | |
| SCHEMBL5176138 | 0.81 | MAPT (0.38) | MEN1KMT2A | |
| SCHEMBL4613179 | 0.81 | — | — | |
| SCHEMBL6473002 | 0.78 | USP2 (0.33) | KDM4E | |
| SCHEMBL17545124 | 0.78 | TDP1 (0.47) | CA1MEN1KMT2ACA12CA2 | |
| SCHEMBL5163572 | 0.76 | APP (0.35) | CHRM2 | |
| SCHEMBL2641885 | 0.74 | APEX1 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194533-A1 | METHOD FOR STABILIZING NITRILASE ACTIVITY AND PRESERVING MICROBIAL CELLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001004278-A1 | METHOD FOR STABILIZING NITRILASE ACTIVITY AND PRESERVING MICROBIAL CELLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-01-18 | — | — | WO | disclosed |