Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176138 | 0.81 | MAPT (0.38) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7553791 | 0.75 | DNM1 (0.46) | TSHRCA2 | |
| SCHEMBL5454493 | 0.75 | DNM1 (0.46) | TSHRCA2 | |
| SCHEMBL7160479 | 0.75 | DNM1 (0.46) | TSHRCA2 | |
| SCHEMBL7567519 | 0.74 | KDM4E (0.36) | MEN1KMT2ACA2 | |
| SCHEMBL17545124 | 0.74 | TDP1 (0.47) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5163572 | 0.72 | APP (0.35) | SMN1; SMN2LMNAALDH1A1TSHR | |
| 1,4-Butanediol SCHEMBL15301979 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| 1,4-Butanediol SCHEMBL130918 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL4374314 | 0.70 | MEN1 (0.43) | MEN1KMT2AATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141703-A1 | COMPOSITIONS AND METHODS FOR SILENCING APOLIPOPROTEIN B | PROTIVA BIOTHERAPEUTICS INC. (CA) | 2011-11-17 | — | — | WO | disclosed |