Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872540 | 0.93 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL9057181 | 0.91 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL24093150 | 0.85 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL20843607 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL21465705 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525011 | 0.80 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525017 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL7696575 | 0.80 | SLC6A2 (0.84) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23514587 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL20979197 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012075-B2 | Cathepsin cysteine protease inhibitors | MERCK & CO., INC. (US) | 2006-03-14 | — | — | US | disclosed |