Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872547 | 0.80 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525047 | 0.80 | IDH2 (0.40) | OPRL1BCHEACHEBACE1IDH2 | |
| SCHEMBL8280205 | 0.78 | LTA4H (0.54) | SLC6A2SLC6A4SLC6A3OPRL1CYP2E1 | |
| SCHEMBL5872540 | 0.74 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525099 | 0.74 | LTA4H (0.62) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL9057181 | 0.73 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525011 | 0.73 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL15525015 | 0.72 | TACR1 (0.41) | KMT2AMEN1RAB9ATACR1BCHE | |
| SCHEMBL477489 | 0.72 | CYP2A6 (0.47) | KMT2AMEN1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL12819940 | 0.72 | CYP2A6 (0.47) | KMT2AMEN1OPRL1CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190092765-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-03-28 | — | — | US | claimed |
| EP-2838893-B1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | claimed |
| CN-104428294-B | N cycloalkyl N [(heterocyclyl phenyl) methylene] (thio) carboxamide derivative | 拜尔农科股份公司 | 2017-07-14 | — | — | CN | claimed |
| US-20150210678-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-07-30 | — | — | US | claimed |
| EP-2838893-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-02-25 | — | — | EP | claimed |
| WO-2013156559-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-10-24 | — | — | WO | claimed |
| US-20190092765-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-03-28 | — | — | US | disclosed |
| EP-2838893-B1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-10125126-B2 | N-cycloalkyl-N-[(heterocyclylphenyl)methylene]-(thio)carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2018-11-13 | — | — | US | disclosed |
| CN-104428294-B | N cycloalkyl N [(heterocyclyl phenyl) methylene] (thio) carboxamide derivative | 拜尔农科股份公司 | 2017-07-14 | — | — | CN | disclosed |
| US-20150210678-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-07-30 | — | — | US | disclosed |
| EP-2838893-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013156559-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210678-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | CBR3, NANP, CBR1 | SLC6A2 4682/4885SLC6A4 4012/4885SLC6A3 4142/4885 |
| US-10125126-B2 | N-cycloalkyl-N-[(heterocyclylphenyl)methylene]-(thio)carboxamide derivatives | CBR3, NANP, CBR1 | SLC6A2 4682/4885SLC6A4 4012/4885SLC6A3 4142/4885 |
| US-20190092765-A1 | N-CYCLOALKYL-N-[(HETEROCYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | CBR3, CBR1, NANP | SLC6A2 4646/4885SLC6A4 3927/4885SLC6A3 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.